Tirzepatide is a new medication that has recently gained widespread interest due to the part it plays in weight loss, especially for those managing type 2 diabetes. This drug works at two different levels: as a dual incretin receptor agonist, influencing the pancreas to release insulin when blood sugar levels are high and reducing the liver’s release of sugar not needed between meals. However, its potential use in weight management may go beyond blood sugar control.
What Is Tirzepatide?
Tirzepatide is a new medication that has just been approved by the FDA for the treatment of type 2 diabetes. It was recognized by its distinct action in the body and also by its contribution to weight loss.
Mechanism of Action of Tirzepatide
It acts both as a dual GIP and GLP-1 receptor agonist. GIP and GLP-1 are incretins, hormones that stimulate insulin secretion in a glucose-dependent manner. Stimulating the receptors, tirzepatide works by increasing endogenous insulin release in response to a meal and decreasing gastric emptying to lower blood glucose.
Weight Loss with Tirzepatide
So far, tirzepatide has resulted in satisfactory management of weight loss and, therefore, has brought new hope for obese individuals. Recent studies have accentuated its efficacy in bringing body weight down considerably.
Appropriate Use and Dosing
Tirzepatide, popularly known by its brand name Mounjaro, is indicated for weight in adults with type 2 diabetes. Its optimal effect depends on appropriate dosing and techniques of administration.
Dosage Initiation and Titration
Generally, it is advised for medical professionals to start treatment with Tirzepatide for weight loss at a low dose of 2.5 mg. It is injected once a week with a pen and can be gradually increased if needed.
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