Female P. operculella use the leaves to put their eggs and the hatched larvae will eat away at the mesophyll of the leaf. Tomatoes were linked to seven Salmonella outbreaks between 1990 and 2005, and may have been the trigger of a salmonellosis outbreak causing 172 sicknesses in 18 US states in 2006. The leaves, stem, and green unripe fruit of the tomato plant include small amounts of the alkaloid tomatine, whose effect on humans has not been studied. They additionally include small quantities of solanine, a toxic alkaloid present in potato leaves and different vegetation in the nightshade family.
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